The "3D Cell Culture Global Market - Forecast to 2024" report has been added to ResearchAndMarkets.com's offering.
The market is expected to grow at a low double digit CAGR to reach $1,485.1 million by 2024.
As intricacies of these techniques are understood advanced 3D models have been developed which greatly influence the in-vitro culturing and driving cell culture market.
In contrast to 2D environment, cells grown in three-dimensions display higher degree of intercellular interactions, assume more physiologically relevant morphologies and preserve higher-order tissue processes. Tools, technologies, and protocols are making in-vitro 3D analysis simple, cheap, reproducible and scalable-enough for adaptation in drug development.
As these tools have become more accessible and validated, researchers in both academia and biopharma are shifting their attention from 2D to 3D cell culture.
Rising investments in research and development, increasing need for organ transplantation, use of 3D cell culture models as a tool against animal testing, use of microfluidic technology, and increasing focus on regenerative medicine are some of the factors that are driving the market growth.
The entry of new players with novel technologies and introduction of technology driven products are creating an opportunity in the global 3D cell culture market. Whereas, Lack of experienced and skilled research professionals, lack of consistency in 3D cell culture products and budget restriction for small and medium-sized laboratories are hindering the market growth.
Stringent regulatory process controls and ethical concern over animal source usage are the major threat to the market.
The recent progress in microfluidic technology, scaffolds, spheroids and gels-based systems is making lot of difference in the market as they provide micro-scale complex structures and well-controlled parameters to mimic the in vivo environment of cells and thereby gives an opportunity for scientists to explore new applications such as tissue engineering, stem cell, drug discovery and regenerative medicine.
The rapid advancements in the field of cell culture such as 3D bioprinting, organ-on-chip, and single use bioreactors is advancing day- by-day and has been accepted as the future direction of 3D cell culture market. Now-a-days, ultra low attachment micro-plates (ULA) applications are increasing as researchers are focusing on single spheroid and microtissue production for downstream assay compatibility driving demand for ultra low attachment microplates. For instance, InSphero AG (Switzerand), Corning Incorporated (U.S.), Perkin Elmer (U.S) are some the major companies manufacturing these plates.
The 3D cell culture technology global market is broadly classified into scaffold based platforms and scaffold free platforms, of which the scaffold based platforms, hold the largest share in 2017. However the scaffold free platforms are expected to grow at a faster rate.
Furthermore scaffolds hold the largest share among the scaffold based platforms that include hydrogels and other products as well. Similarly, the forced floating method occupied the largest share within the scaffold free market when compared to the other methods such as hanging drop method, agitation based methods and microfluidics.
A number of product categories are available in the 3D cell culture market that include cells & tissues, media, sera and reagents, microplates and others, assay kits, scaffolds and other products. The media, sera and reagents segment occupy the largest share in 2017. However the scaffolds market seems to be the fastest growing, due to the advancements in technologies in this area including the uptake of bioprinting technology.
There are a number of applications in which 3D cell culture products are used that include basic research, toxicity and drug safety screening, tissue engineering, stem cell research, drug discovery, gene therapy and cancer research. The toxicity and drug safety screening is a field in which recent advanced are recognized making it the largest segment in 2017.
From an end-users perspective the biotechnology and pharmaceutical industries occupy the largest share in 2017 followed by CROs and hospitals is growing at the fast rate.
Geographically, 3D cell culture market is divided into North America, Europe, Asia-Pacific and Rest of the world. North America dominated the market with largest share in 2017, due to increased government funding, rising incidence of cancer, development of new models for candidate drug screening and cytotoxicity testing, expanding biopharmaceutical industries and high healthcare expenditure.
Europe accounts for second largest share followed by Asia-pacific region and it is expected to grow at the highest rate due to increased healthcare awareness, improved economic growth, low operating cost and increased outsourcing. Significant new product launches, collaborations and partnerships joint ventures are some of the industry trends that are playing a major role for the market growth.
Key Topics Covered:
1. Executive Summary
3. Market Analysis
3.2 Market Segmentation
3.3 Factors Influencing Market
3.3.1 Drivers And Opportunities
220.127.116.11 Substantial R&D Investments For 3D Cell Culture
18.104.22.168 Use Of 3D Cell Culture Models In Drug Discovery And Research As An Alternative To Animal Testing
22.214.171.124 Emergence Of Microfluidic Technology And Bioprinting
126.96.36.199 Increasing Focus On Regenerative Medicine
3.3.2 Restraints And Threats
188.8.131.52 Lack Of Experienced And Skilled Professionals
184.108.40.206 Budget Restriction For Small And Medium Sized Laboratories And Lack Of Consistency In 3D Cell Culture Products
220.127.116.11 Stringent Process Controls For Advanced Handling Capabilities
18.104.22.168 Ethical Concern Over Use Of Animal Sources
3.4 Regulatory Affairs
3.4.1 United States
3.5 Technological Advancements
3.5.3 3D Bioprinting
3.5.4 Single Use Reactors
3.6 Porter'S Five Force Analysis
3.6.1 Threat Of New Entrants
3.6.2 Threat Of Substitutes
3.6.3 Bargaining Power Of Suppliers
3.6.4 Bargaining Power Of Buyers
3.6.5 Rivalry Among Existing Competitors
3.7 Supply Chain Analysis
3.7.1 Raw Material Supplier:
3.7.2 Product Manufacturers:-
3.7.3 3D Cell Culture Products Distributors
3.8 Market Share Analysis By Major Players
4. 3D Cell Culture Global Market, By Technology
4.2 Scaffold Based Platforms
4.3 Scaffold Free Platforms
4.3.1 Hang Drop Method
4.3.2 Forced Floating
4.3.3 Agitation Based Methods
5. 3D Cell Culture Global Market, By Products
5.2 Cells And Tissues
5.3 Media, Sera And Reagents
5.4 Microplates And Others
5.5 Assay Kits
5.6.1 Natural Scaffolds
5.6.2 Synthetic Scaffolds
5.6.3 Hybrid Composite
6. 3D Cell Culture Global Market, By Application
6.2 Basic Research
6.3 Toxicity And Drug Safety Screening
6.4 Tissue Engineering
6.5 Stem Cell Research
6.6 Drug Discovery
6.7 Cancer Research
6.8 Gene Therapy
7. 3D Cell Culture Global Market, By End-Users
7.2 Academic Institutes
7.3 Biotechnology And Pharmaceutical Industries
8. Regional Analysis
8.2 North America
8.5 Rest Of The World
8.5.2 Rest Of Latin America
8.5.3 Middle East And Others
9. Competitive Landscape
9.2 Collaborations & Partnerships
9.3 New Product Launches
9.4 Agreements, Expantions & Mergers
9.5 Company Matrix
10. Major Companies
- 3D Matrix Co (Japan)
- AMSBio LLC (U.S.)
- Ascendance (U.S.)
- Becton Dickenson & Company (U.S.)
- BioCellChallenge (France)
- Biolamina AB (Sweden)
- CellecBiotek AG (Switzerland)
- CelVivo IVS (Denmark)
- Corning (U.S.)
- Cytoo (France)
- Fujifilm (Japan)
- Hurel Corp (U.S.)
- Insphero (Switzerland)
- JSR Corporation (Organogenix Inc.)(Japan)
- Kuraray Co. Ltd. (Japan)
- Lonza (Switzerland)
- Merck KGaA (Germany)
- Nano 3D Biosciences (U.S.)
- Nanopahrma AS (Czech Republic)
- Organovo Holdings Inc. (U.S.).
- Prodizen (Korea)
- Thermofisher Scientific (U.S.)
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